Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 20/20 | 0.89 |
| ▸ | ADRB2 | P07550 | 12/20 | 0.89 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.89 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7678634 | 0.94 | ADRB3 (1.00) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7674986 | 0.94 | ADRB3 (1.00) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7674992 | 0.94 | ADRB3 (1.00) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7670221 | 0.94 | ADRB3 (1.00) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7675887 | 0.94 | ADRB3 (1.00) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7677225 | 0.92 | ADRB3 (0.86) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7677219 | 0.92 | ADRB3 (0.86) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7671775 | 0.92 | ADRB3 (0.91) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7671776 | 0.92 | ADRB3 (0.91) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7674878 | 0.91 | ADRB3 (1.00) | ADRB3ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436914-B1 | TREATING DIABETES, OBESITY, DEPRESSION, ACHALASIA OR INTESTINAL HYPERMOTILITY DISORDERS | BRISTOL-MYERS SQUIBB COMPANY | 2002-08-20 | — | — | US | disclosed |