Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 3/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | PNP | P00491 | 4/20 | 0.52 |
| ▸ | TK1 | P04183 | 2/20 | 0.49 |
| ▸ | AHCY | P23526 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | EDNRA | P25101 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | VCP | P55072 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lobucavir SCHEMBL598707 | 1.00 | HPRT1 (0.53) | HPRT1ADORA3PNPTK1AHCY | |
| Lobucavir SCHEMBL5990162 | 1.00 | HPRT1 (0.53) | HPRT1ADORA3PNPTK1AHCY | |
| Lobucavir SCHEMBL10460499 | 1.00 | HPRT1 (0.53) | HPRT1ADORA3PNPTK1AHCY | |
| Lobucavir SCHEMBL51919 | 1.00 | HPRT1 (0.53) | HPRT1ADORA3PNPTK1AHCY | |
| Lobucavir SCHEMBL418430 | 1.00 | HPRT1 (0.53) | HPRT1ADORA3PNPTK1AHCY | |
| Lobucavir SCHEMBL9615453 | 1.00 | HPRT1 (0.53) | HPRT1ADORA3PNPTK1AHCY | |
| Lobucavir SCHEMBL9615451 | 1.00 | HPRT1 (0.53) | HPRT1ADORA3PNPTK1AHCY | |
| Lobucavir SCHEMBL15630215 | 1.00 | HPRT1 (0.53) | HPRT1ADORA3PNPTK1AHCY | |
| Lobucavir SCHEMBL51918 | 1.00 | HPRT1 (0.53) | HPRT1ADORA3PNPTK1AHCY | |
| Lobucavir SCHEMBL7166488 | 1.00 | HPRT1 (0.53) | HPRT1ADORA3PNPTK1AHCY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348586-B1 | NUCLEOTIDE SEQUENCE OF HERPES VIRUS; DIAGNOSIS; VACCINES; VIRICIDES; ANTISENSE AGENTS; TRIPLEX OLIGONUCLEOTIDES; | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2002-02-19 | — | — | US | disclosed |
| EP-0358154-B1 | Novel cyclobutane derivative and process for producing same | NIPPON KAYAKU KK (JP) | 1998-12-02 | — | — | EP | disclosed |
| US-5246931-A | Triazine-substituted cyclobutane derivatives; viricides; side effect reduction | BRISTOL-MYERS SQUIBB COMPANY (US) | 1993-09-21 | — | — | US | disclosed |
| US-5198583-A | Optically active cyclobutane nucleoside and intermediates, therefor | E. R. SQUIBB & SONS, INC. (US) | 1993-03-30 | — | — | US | disclosed |
| US-5153352-A | Viricides and antitumor agent | BRISTOL-MYERS SQUIBB COMPANY (US) | 1992-10-06 | — | — | US | disclosed |
| US-5064961-A | PROCESS FOR PREPARING AN OPTICALLY ACTIVE CYCLOBUTANE NUCLEOSIDE | E. R. SQUIBB & SONS, INC. (US) | 1991-11-12 | — | — | US | disclosed |
| EP-0366059-A2 | Carbocyclic nucleoside analogs | BRISTOL-MYERS SQUIBB COMPANY (US) | 1990-05-02 | — | — | EP | disclosed |
| EP-0358154-A2 | Novel cyclobutane derivative and process for producing same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1990-03-14 | — | — | EP | disclosed |