Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968690 | 0.81 | AOC3 (0.38) | HTR2AAOC3SLC6A4CYP1A2SLC6A2 | |
| SCHEMBL13569341 | 0.81 | AOC3 (0.42) | AOC3TAAR1CYP1A2 | |
| SCHEMBL18257696 | 0.81 | AOC3 (0.42) | AOC3TAAR1CYP1A2 | |
| SCHEMBL13569343 | 0.81 | AOC3 (0.42) | AOC3TAAR1CYP1A2 | |
| SCHEMBL12454628 | 0.79 | AOC3 (0.62) | AOC3SLC6A4IDO1SLC6A2SLC6A3 | |
| SCHEMBL13569328 | 0.79 | AOC3 (0.62) | AOC3SLC6A4TAAR1CYP1A2SLC6A2 | |
| SCHEMBL4199855 | 0.79 | AOC3 (0.62) | AOC3SLC6A4IDO1SLC6A2SLC6A3 | |
| SCHEMBL8250743 | 0.79 | CYP1A2 (0.38) | HTR2AAOC3SLC6A4CYP1A2ALOX5 | |
| SCHEMBL8250967 | 0.79 | SLC6A4 (0.38) | HTR2AAOC3SLC6A4IDO1CYP1A2 | |
| SCHEMBL8168288 | 0.79 | CYP1A2 (0.38) | HTR2AAOC3SLC6A4CYP1A2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002072547-A1 | AMINATION PROCESS | ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE, INC. (US) | 2002-09-19 | — | — | WO | disclosed |