Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2595879 | 0.86 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2596304 | 0.83 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2596295 | 0.82 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2596020 | 0.79 | PDE10A (0.68) | PDE10A | |
| SCHEMBL2596164 | 0.79 | PDE10A (0.67) | PDE10A | |
| SCHEMBL2596158 | 0.77 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2590566 | 0.77 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2595775 | 0.76 | PDE10A (1.00) | PDE10A | |
| SCHEMBL7698016 | 0.75 | PDE10A (0.62) | PDE10A | |
| SCHEMBL2596148 | 0.75 | PDE10A (1.00) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011143365-A1 | NITROGEN HETEROCYCLIC COMPOUNDS USEFUL AS PDE10 INHIBITORS | AMGEN INC. (US) | 2011-11-17 | — | — | WO | disclosed |