Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 19/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 17/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7094978 | 1.00 | ADRB3 (0.55) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7699121 | 0.87 | ADRB3 (0.61) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7091280 | 0.87 | ADRB3 (0.61) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7090763 | 0.87 | ADRB3 (0.75) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7594191 | 0.86 | ADRB3 (0.61) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7093799 | 0.86 | ADRB3 (0.61) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7095373 | 0.86 | ADRB3 (0.51) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7702425 | 0.86 | ADRB3 (0.51) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7094211 | 0.86 | ADRB3 (0.73) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7094210 | 0.86 | ADRB3 (0.73) | ADRB3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002006229-A2 | HETEROCYCLIC BETA-3 ADRENERGIC RECEPTOR AGONISTS | WYETH (US) | 2002-01-24 | — | — | WO | disclosed |