Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.50 |
| ▸ | HRH1 | P35367 | 3/20 | 0.50 |
| ▸ | DRD3 | P35462 | 3/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | MLNR | O43193 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30720033 | 0.99 | SLC29A1 (0.60) | SLC29A1MEN1KMT2ALMNAHTR2A | |
| Hydrochloric Acid SCHEMBL7705419 | 0.98 | SLC29A1 (0.59) | SLC29A1MEN1KMT2ALMNAHTR2A | |
| Mioflazine SCHEMBL611300 | 0.92 | SLC29A1 (0.68) | SLC29A1MEN1KMT2ALMNAHTR2A | |
| Mioflazine SCHEMBL124029 | 0.92 | SLC29A1 (0.70) | SLC29A1MEN1KMT2ALMNAHTR2A | |
| Mioflazine SCHEMBL8675598 | 0.91 | SLC29A1 (0.69) | SLC29A1MEN1KMT2ALMNAHTR2A | |
| SCHEMBL10459776 | 0.91 | SLC29A1 (0.65) | SLC29A1MEN1KMT2ALMNAHTR2A | |
| Mioflazine SCHEMBL119416 | 0.91 | SLC29A1 (0.68) | SLC29A1MEN1KMT2ALMNAHTR2A | |
| Hydrochloric Acid SCHEMBL10459779 | 0.90 | SLC29A1 (0.63) | SLC29A1MEN1KMT2ALMNAHTR2A | |
| SCHEMBL10681498 | 0.86 | SLC29A1 (0.60) | SLC29A1MEN1KMT2ALMNAHTR2A | |
| Hydrochloric Acid SCHEMBL10678583 | 0.83 | SLC29A1 (0.81) | SLC29A1MEN1KMT2ALMNAHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403589-B1 | NUCLEOSIDE TRANSPORT INHIBITOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2002-06-11 | — | — | US | disclosed |
| EP-0999840-A1 | USE OF DRAFLAZINE-ANALOGUES FOR TREATING PAIN | JANSSEN PHARMACEUTICA N.V. (BE) | 2000-05-17 | — | — | EP | disclosed |
| WO-1998057643-A1 | USE OF DRAFLAZINE-ANALOGUES FOR TREATING PAIN | JANSSEN PHARMACEUTICA N.V. (BE) | 1998-12-23 | — | — | WO | disclosed |