Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | UNG | P13051 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11100762 | 0.94 | TDP1 (0.52) | TDP1CA12CA1CA2CA6 | |
| SCHEMBL9421257 | 0.88 | TDP1 (0.62) | TDP1CA12CA1CA2CA6 | |
| SCHEMBL6139473 | 0.86 | TDP1 (0.50) | TDP1CA12CA1CA2CA6 | |
| SCHEMBL209607 | 0.86 | TDP1 (0.71) | TDP1CA12CA1CA2CA6 | |
| SCHEMBL17978154 | 0.86 | TDP1 (0.50) | TDP1CA12CA1CA2CA6 | |
| SCHEMBL27574211 | 0.86 | TDP1 (0.60) | TDP1CA12CA1CA2CA6 | |
| SCHEMBL9436550 | 0.85 | TDP1 (0.69) | TDP1KMT2A | |
| SCHEMBL557443 | 0.85 | CYP2C9 (0.62) | CA12CA1CA2CA9CYP2C9 | |
| SCHEMBL10867635 | 0.85 | TDP1 (0.69) | TDP1KMT2A | |
| SCHEMBL212972 | 0.85 | TDP1 (0.69) | TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0105825-B1 | MULTI-LAYER POLYISOPHTHALATE AND POLYTEREPHTHALATE ARTICLES AND PROCESS THEREFOR | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1987-11-04 | — | — | EP | claimed |
| EP-1189984-A1 | BLENDS OF POLYESTER COPOLYMER AND ETHYLENE VINYL ACETATE WITH IMPROVED GAS BARRIER PROPERTIES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000075224-A1 | BLENDS OF POLYESTER COPOLYMER AND ETHYLENE VINYL ACETATE WITH IMPROVED GAS BARRIER PROPERTIES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-12-14 | — | — | WO | disclosed |
| US-5434239-A | Esterification, condensation polymerization | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-07-18 | — | — | US | disclosed |