Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 20/20 | 0.65 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.65 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7130776 | 1.00 | ADRB3 (0.65) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7138168 | 0.92 | ADRB3 (0.65) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7133458 | 0.88 | ADRB3 (0.83) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7699700 | 0.88 | ADRB3 (0.83) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7133320 | 0.87 | ADRB3 (0.66) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7689563 | 0.86 | ADRB3 (0.51) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7130781 | 0.80 | ADRB3 (0.51) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7134587 | 0.80 | ADRB3 (0.80) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7135095 | 0.80 | ADRB3 (0.80) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7138803 | 0.80 | ADRB3 (0.83) | ADRB3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002006255-A2 | HYDROXY-(PIPERIDIN-4-YL-METHYLAMINO)-ALKYL BETA-3 ADRENERGIC RECEPTOR ANTAGONISTS | WYETH (US) | 2002-01-24 | — | — | WO | disclosed |