Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 18/20 | 0.50 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702727 | 0.95 | PARP1 (0.54) | PARP1PARP2 | |
| SCHEMBL5665661 | 0.89 | PARP1 (0.52) | PARP1PARP2 | |
| SCHEMBL5622266 | 0.87 | PARP1 (0.62) | PARP1PARP2 | |
| SCHEMBL5620744 | 0.86 | PARP1 (0.70) | PARP1PARP2 | |
| SCHEMBL5620739 | 0.86 | PARP1 (0.70) | PARP1PARP2 | |
| SCHEMBL6781561 | 0.85 | PARP1 (0.50) | PARP1PARP2 | |
| SCHEMBL5621054 | 0.82 | PARP1 (0.63) | PARP1PARP2 | |
| SCHEMBL5620556 | 0.82 | PARP1 (0.69) | PARP1PARP2 | |
| SCHEMBL5621511 | 0.82 | PARP1 (0.70) | PARP1PARP2 | |
| Hydrochloric Acid SCHEMBL18614332 | 0.81 | PARP1 (0.62) | PARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448271-B1 | SUCH AS 2-(PIPERIDIN-4-YL)BENZIMIDAZOLE-4-CARBOXAMIDE; INHIBITORS OF ENZYME POLY(ADP-RIBOSE)POLYMERASE; IMPROVED WATER SOLUBILITY | BASF AKTIENGESELLSCHAFT (DE) | 2002-09-10 | — | — | US | disclosed |