Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7091164 | 0.88 | CHEK1 (0.50) | CHEK1KDR | |
| SCHEMBL7090796 | 0.85 | CHEK1 (0.46) | CHEK1KDR | |
| SCHEMBL7704425 | 0.80 | KDR (0.52) | CHEK1KDR | |
| SCHEMBL6999873 | 0.79 | KDR (0.50) | CHEK1KDR | |
| SCHEMBL7096426 | 0.78 | CHEK1 (0.54) | CHEK1KDR | |
| SCHEMBL7698827 | 0.73 | CHEK1 (0.57) | CHEK1KDR | |
| SCHEMBL7094716 | 0.73 | CHEK1 (0.51) | CHEK1KDR | |
| SCHEMBL7003703 | 0.72 | KDR (0.55) | CHEK1KDR | |
| SCHEMBL7702171 | 0.72 | CHEK1 (0.61) | CHEK1KDR | |
| SCHEMBL7704080 | 0.72 | CHEK1 (0.48) | CHEK1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1127051-A2 | TRICYCLIC PYRAZOLE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2001-08-29 | — | — | EP | claimed |
| WO-2000027822-A2 | TRICYCLIC PYRAZOLE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-18 | — | — | WO | claimed |
| US-6462036-B1 | INHIBITING SIGNAL TRANSDUCTION BY MODULATING ACTIVITY OF RECEPTOR AND NONRECEPTOR TYROSINE AND SERINE/THREONINE KINASES TO REGULATE AND MODULATE ABNORMAL OR INAPPROPRIATE CELL PROLIFERATION, DIFFERENTIATION, OR METABOLISM | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-08 | — | — | US | disclosed |
| EP-1127051-A2 | TRICYCLIC PYRAZOLE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2001-08-29 | — | — | EP | disclosed |
| WO-2000027822-A2 | TRICYCLIC PYRAZOLE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-18 | — | — | WO | disclosed |