Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 13/20 | 0.58 |
| ▸ | PGR | P06401 | 11/20 | 0.58 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.53 |
| ▸ | SHBG | P04278 | 2/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6836544 | 1.00 | AR (0.58) | ARPGRNR3C2SHBGSLC22A1 | |
| SCHEMBL7700797 | 1.00 | AR (0.58) | ARPGRNR3C2SHBGSLC22A1 | |
| SCHEMBL6836545 | 1.00 | AR (0.58) | ARPGRNR3C2SHBGSLC22A1 | |
| SCHEMBL13770171 | 0.89 | AR (0.58) | ARPGRNR3C2CYP19A1 | |
| SCHEMBL13770500 | 0.86 | AR (0.56) | ARPGRNR3C2SHBGSLC22A1 | |
| SCHEMBL4107737 | 0.85 | AR (0.57) | ARPGRNR3C2SHBGCYP19A1 | |
| SCHEMBL4112702 | 0.85 | AR (0.57) | ARPGRNR3C2SHBGCYP19A1 | |
| SCHEMBL11857527 | 0.85 | AR (0.71) | ARPGRNR3C2SHBGSLC22A1 | |
| SCHEMBL11865080 | 0.85 | AR (0.71) | ARPGRNR3C2SHBGSLC22A1 | |
| SCHEMBL6693185 | 0.85 | AR (0.71) | ARPGRNR3C2SHBGSLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212345-A2 | ORALLY ACTIVE 7.ALPHA.-ALKYL ANDROGENS | Akzo Nobel N.V. (NL) | 2002-06-12 | — | — | EP | disclosed |
| WO-2000059920-A2 | ORALLY ACTIVE 7.ALPHA.-ALKYL ANDROGENS | AKZO NOBEL N.V. (NL) | 2000-10-12 | — | — | WO | disclosed |