Known targets — ChEMBL curated mechanism
SLC6A2SLC6A3SSTR1SSTR2SSTR3SSTR5
The experimentally established mechanism targets of Aspartic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 4/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CPT2 | P23786 | 1/20 | 0.41 |
| ▸ | CPT1A | P50416 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.30 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.30 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | GSR | P00390 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aspartic Acid SCHEMBL1459004 | 0.97 | — | — | |
| Aspartic Acid SCHEMBL2560053 | 0.97 | — | — | |
| Aspartic Acid SCHEMBL161238 | 0.97 | CA4 (0.48) | CA4CTSLCPT2CPT1ACA2 | |
| Aspartic Acid SCHEMBL161240 | 0.97 | CA4 (0.48) | CA4CTSLCPT2CPT1ACA2 | |
| Aspartic Acid SCHEMBL1303171 | 0.95 | CA4 (0.46) | CA4CTSLCPT2CPT1ACA2 | |
| Aspartic Acid SCHEMBL30939427 | 0.95 | CA4 (0.46) | CA4CTSLCPT2CPT1ACA2 | |
| Aspartic Acid SCHEMBL1300891 | 0.95 | CA4 (0.46) | CA4CTSLCPT2CPT1ACA2 | |
| Aspartic Acid SCHEMBL1301888 | 0.95 | CA4 (0.46) | CA4CTSLCPT2CPT1ACA2 | |
| Aspartic Acid SCHEMBL1302392 | 0.95 | CA4 (0.46) | CA4CTSLCPT2CPT1ACA2 | |
| Aspartic Acid SCHEMBL1301522 | 0.95 | CA4 (0.46) | CA4CTSLCPT2CPT1ACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355771-B1 | MODIFIED BY MERCAPTOALKYLAMINE; CORROSION RESISTANCE, ANTISCALING AGENTS | NIPPON SHOKUBAI CO., LTD. (JP) | 2002-03-12 | — | — | US | disclosed |
| EP-0980883-A1 | Modified polyaspartic acid, method for production thereof and use therefor | Nippon Shokubai Co., Ltd. (JP) | 2000-02-23 | — | — | EP | disclosed |