Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | PEPD | P12955 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28270632 | 1.00 | CA4 (0.48) | CA4PEPDHCAR2KEAP1NFE2L2 | |
| SCHEMBL23620761 | 0.88 | CA4 (0.43) | CA4PEPDFDPSBLMTDP1 | |
| SCHEMBL5928132 | 0.87 | HCAR2 (0.46) | CA4PEPDHCAR2KEAP1NFE2L2 | |
| SCHEMBL28263586 | 0.87 | HCAR2 (0.46) | CA4PEPDHCAR2KEAP1NFE2L2 | |
| SCHEMBL8651558 | 0.84 | CA4 (0.40) | CA4PEPDFDPSBLMTDP1 | |
| SCHEMBL13268919 | 0.84 | CA4 (0.40) | CA4PEPDHCAR2KEAP1NFE2L2 | |
| SCHEMBL13268921 | 0.84 | CA4 (0.40) | CA4PEPDHCAR2KEAP1NFE2L2 | |
| SCHEMBL14720437 | 0.82 | PEPD (0.39) | CA4PEPD | |
| SCHEMBL28523234 | 0.82 | PEPD (0.35) | CA4PEPD | |
| SCHEMBL20854281 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104773847-B | Phosphono copolymer of maleic anhydride and acrylic acid and preparation method thereof, application | 中冶华天工程技术有限公司 | 2016-07-20 | — | — | CN | claimed |
| CN-85103418-A | Preparation method of dihydropyridine-3, 5-dicarboxylic ester derivative | — | 1986-10-15 | — | — | CN | claimed |
| CN-104773847-B | Phosphono copolymer of maleic anhydride and acrylic acid and preparation method thereof, application | 中冶华天工程技术有限公司 | 2016-07-20 | — | — | CN | disclosed |
| EP-1165487-A1 | DERIVATIVES OF VENLAFAXINE AND METHODS OF PREPARING AND USING THE SAME | Sepracor Inc. (US) | 2002-01-02 | — | — | EP | disclosed |
| EP-1135359-A1 | DERIVATIVES OF (-)-VENLAFAXINE AND METHODS OF PREPARING AND USING THE SAME | Sepracor Inc. (US) | 2001-09-26 | — | — | EP | disclosed |
| EP-1135358-A1 | DERIVATIVES OF (+)-VENLAFAXINE AND METHODS OF PREPARING AND USING THE SAME | Sepracor Inc. (US) | 2001-09-26 | — | — | EP | disclosed |
| WO-2000059851-A1 | DERIVATIVES OF VENLAFAXINE AND METHODS OF PREPARING AND USING THE SAME | SEPRACOR INC. (US) | 2000-10-12 | — | — | WO | disclosed |
| WO-2000032556-A1 | DERIVATIVES OF (-)-VENLAFAXINE AND METHODS OF PREPARING AND USING THE SAME | SEPRACOR INC. (US) | 2000-06-08 | — | — | WO | disclosed |
| WO-2000032555-A1 | DERIVATIVES OF (+)-VENLAFAXINE AND METHODS OF PREPARING AND USING THE SAME | SEPRACOR INC. (US) | 2000-06-08 | — | — | WO | disclosed |