Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.42 |
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 3/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | DHPS | P49366 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700309 | 0.91 | MCHR1 (0.44) | MCHR1HTR2CPIK3CGHTR2APDE4A | |
| SCHEMBL8711302 | 0.91 | HTR2C (0.44) | MCHR1HTR2CPIK3CGLMNAPDE4A | |
| SCHEMBL7693775 | 0.90 | MCHR1 (0.44) | MCHR1HTR2CPIK3CGHTR2APDE4A | |
| SCHEMBL7699082 | 0.89 | MCHR1 (0.43) | MCHR1HTR2CPIK3CGHTR2APDE4A | |
| SCHEMBL7699175 | 0.88 | MCHR1 (0.45) | MCHR1HTR2CPIK3CGHTR2ALMNA | |
| SCHEMBL7700748 | 0.88 | MCHR1 (0.44) | MCHR1HTR2CPIK3CGHTR2APDE4A | |
| SCHEMBL7700767 | 0.88 | MCHR1 (0.42) | MCHR1HTR2CPIK3CGHTR2APDE4A | |
| SCHEMBL7705901 | 0.86 | MCHR1 (0.42) | MCHR1HTR2CPIK3CGHTR2ALMNA | |
| SCHEMBL7696526 | 0.86 | MCHR1 (0.41) | MCHR1HTR2CPIK3CGHTR2APDE4A | |
| SCHEMBL8707222 | 0.86 | MCHR1 (0.45) | MCHR1HTR2CPIK3CGHTR2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002081446-A1 | 3-CYCLOPENTYLOXY-4-METHOXYPHENYL-ISOINDOLINONE DERIVATIVES AND THE USE THEREOF | DAEWOONG CO., LTD. (KR) | 2002-10-17 | — | — | WO | disclosed |