Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | HMGCR | P04035 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1716224 | 0.83 | CHRM1 (0.39) | TSHRCHRM1ADRA1ATDP1AKR1A1 | |
| SCHEMBL7746912 | 0.83 | CYP2C19 (0.44) | CYP2D6TSHRCYP2C19HIF1ACHRM1 | |
| SCHEMBL8939038 | 0.82 | CHRM1 (0.38) | TSHRCHRM1ADRA1ATDP1AKR1A1 | |
| SCHEMBL8939046 | 0.82 | CHRM1 (0.38) | TSHRCHRM1ADRA1ATDP1AKR1A1 | |
| SCHEMBL10794867 | 0.79 | CHRM1 (0.41) | CYP2D6TSHRCYP2C19HIF1ACHRM1 | |
| SCHEMBL2231038 | 0.76 | CYP2C19 (0.50) | CYP2D6TSHRCYP2C19HIF1ACHRM1 | |
| SCHEMBL8764975 | 0.74 | CHRM1 (0.42) | TSHRCHRM1ADRA1ATDP1AKR1A1 | |
| SCHEMBL6067583 | 0.74 | CHRM1 (0.42) | TSHRCHRM1ADRA1ATDP1AKR1A1 | |
| SCHEMBL1245572 | 0.74 | CHRM1 (0.42) | TSHRCHRM1ADRA1ATDP1AKR1A1 | |
| SCHEMBL21268905 | 0.72 | CHRM1 (0.41) | TSHRCHRM1ADRA1ATDP1AKR1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028829-A2 | PEPTIDE DEFORMYLASE INHIBITORS | QUESTCOR PHARMACEUTICALS, INC. (US) | 2002-04-11 | — | — | WO | disclosed |