Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7818543 | 0.83 | CYP1A2 (0.46) | RAB9ANPC1KMT2AMEN1LMNA | |
| SCHEMBL4810291 | 0.81 | KDM4E (0.42) | KMT2AKDM4EMEN1MAPTSMN1; SMN2 | |
| SCHEMBL7699598 | 0.81 | KDM4E (0.49) | RAB9ANPC1KMT2AKDM4EMEN1 | |
| SCHEMBL13903600 | 0.81 | HSP90AA1 (0.49) | RAB9ANPC1KMT2AKDM4EMEN1 | |
| SCHEMBL11184601 | 0.75 | NPSR1 (0.47) | RAB9ANPC1KMT2AKDM4EMEN1 | |
| SCHEMBL7695788 | 0.75 | KDM4E (0.38) | RAB9ANPC1KMT2AKDM4EMEN1 | |
| SCHEMBL7699109 | 0.74 | CYP1A2 (0.50) | RAB9ANPC1KMT2AKDM4EMEN1 | |
| SCHEMBL4802465 | 0.74 | CNR1 (0.39) | KMT2AKDM4EMEN1MAPTTDP1 | |
| SCHEMBL5179315 | 0.73 | POLB (0.42) | RAB9AKDM4EMAPK1POLBCYP2C9 | |
| SCHEMBL7699107 | 0.72 | IKBKB (0.43) | RAB9ANPC1KMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083650-A1 | NOVEL SULFONYLAMINO-PYRIMIDINES | ACTELION PHARMACEUTICALS LTD (CH) | 2002-10-24 | — | — | WO | disclosed |