Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 11/20 | 0.66 |
| ▸ | MAPK9 | P45984 | 10/20 | 0.66 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.61 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.32 |
| ▸ | QPCT | Q16769 | 1/20 | 0.32 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2886059 | 0.97 | MAPK10 (0.69) | MAPK10MAPK9MAPK8MGLLMEN1 | |
| SCHEMBL2886417 | 0.82 | MAPK10 (0.81) | MAPK10MAPK9MAPK8MEN1ALDH1A1 | |
| Acetonitrile SCHEMBL7707016 | 0.81 | MAPK10 (0.66) | MAPK10MAPK9MAPK8MEN1ALDH1A1 | |
| SCHEMBL2886459 | 0.80 | MAPK10 (0.70) | MAPK10MAPK9MAPK8MEN1ALDH1A1 | |
| SCHEMBL2884064 | 0.80 | MAPK10 (0.69) | MAPK10MAPK9MAPK8MEN1ALDH1A1 | |
| SCHEMBL1518642 | 0.80 | MAPK10 (1.00) | MAPK10MAPK9MAPK8MEN1ALDH1A1 | |
| SCHEMBL4020743 | 0.80 | MAPK10 (0.81) | MAPK10MAPK9MAPK8MEN1ALDH1A1 | |
| SCHEMBL4026579 | 0.80 | MAPK10 (0.71) | MAPK10MAPK9MAPK8MKNK1 | |
| SCHEMBL4024346 | 0.79 | MAPK10 (0.68) | MAPK10MAPK9MAPK8MEN1ALDH1A1 | |
| SCHEMBL2883660 | 0.79 | MAPK10 (0.68) | MAPK10MAPK9MAPK8QPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240164-A1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | Applied Research Systems ARS Holding N.V. (AN) | 2002-09-18 | — | — | EP | claimed |
| WO-2001047920-A1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-07-05 | — | — | WO | claimed |