Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.52 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | MC3R | P41968 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27923673 | 0.80 | — | — | |
| SCHEMBL28346821 | 0.79 | KDM4E (0.45) | KDM4ENAPRTHCAR2BAZ2BADORA3 | |
| SCHEMBL24505646 | 0.77 | KDM4E (0.44) | KDM4ENAPRTHCAR2BAZ2BADORA3 | |
| SCHEMBL14903392 | 0.76 | — | — | |
| SCHEMBL3504579 | 0.76 | — | — | |
| SCHEMBL29993937 | 0.76 | — | — | |
| SCHEMBL31039494 | 0.76 | — | — | |
| SCHEMBL78340 | 0.76 | — | — | |
| SCHEMBL28205980 | 0.76 | — | — | |
| SCHEMBL27650044 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6428624-B1 | MIXTURE OF REDUCING SUGAR AND BASE CATALYST; MIXTURE ENRICHED IN AT LEAST ONE AMINO ACID OF SERINE, THREONINE, VALINE, LEUCINE AND ISOLEUCINE | R. J. REYNOLDS TOBACCO CO. | 2002-08-06 | — | — | US | disclosed |
| US-20020074008-A1 | Method of providing flavorful and aromatic compounds | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2002-06-20 | — | — | US | disclosed |