SCHEMBL7702157

SCHEMBL7702157

Nc1nc2c(ncn2OCc2ccccc2)c(=O)[nH]1

nearest known ligand 0.64

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PNP P00491 11/20 0.64
XDH P47989 7/20 0.57
HPRT1 P00492 1/20 0.50
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
USP2 O75604 1/20 0.47
TSHR P16473 1/20 0.47
EDNRA P25101 1/20 0.47
HTR2A P28223 1/20 0.47
RECQL P46063 1/20 0.47
BLM P54132 1/20 0.47
HBB P68871 1/20 0.47
HSD17B10 Q99714 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL17186409 0.99 PNP (0.62) PNPXDHHPRT1MEN1KMT2A
SCHEMBL9187381 0.88 PNP (0.56) PNPXDHHPRT1USP2TSHR
SCHEMBL27973331 0.86 PNP (0.59) PNPXDHHPRT1MEN1KMT2A
SCHEMBL15643286 0.80 MEN1 (0.58) PNPXDHHPRT1MEN1KMT2A
SCHEMBL8781788 0.79 PNP (0.64) PNPXDHHPRT1MEN1KMT2A
SCHEMBL9184448 0.79 PNP (0.51) PNPXDHHPRT1MEN1KMT2A
SCHEMBL5860317 0.79 PNP (0.59) PNPXDHHPRT1MEN1KMT2A
SCHEMBL18249 0.78 PNP (1.00) PNPXDH
SCHEMBL27503506 0.78 PNP (0.53) PNPXDHHPRT1MEN1KMT2A
SCHEMBL9184456 0.78 PNP (0.49) PNPXDHHPRT1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5525726-A Process for the preparation of an antiviral agent E. R. SQUIBB & SONS, INC. (US) 1996-06-11 US claimed
US-5516903-A Process for preparing [IR-(1α,2β-3α)]-2-amino-9-[2,3-bis(hydroxymethyl)cyclobutyl]-1,9-dihydro-6H-purin-6-one E. R. SQUIBB & SONS, INC. (US) 1996-05-14 US claimed
CN-117924514-B Probe system for detecting cholesterol and application thereof 重庆医科大学 2025-04-04 CN disclosed
CN-117924514-A Probe system for detecting cholesterol and application thereof 重庆医科大学 2024-04-26 CN disclosed
US-6353122-B1 IN CYCLOHEXANONE WITH POTASSIUM PEROXYMONOSULFATE AND SUBSEQUENT REARRANGEMENT TO PROVIDE THE CORRESPONDING CYCLOBUTANONE BRISTOL-MYERS SQUIBB COMPANY 2002-03-05 US disclosed
CN-1040426-C Process for preparing diprotected 2,3-hydroxymethyl cyclobutanol SQUIBB & SONS INC (US) 1998-10-28 CN disclosed
WO-1998038184-A1 A METHOD FOR EPOXIDATION OF 3-METHYLENECYCLOPROPANES BRISTOL-MYERS SQUIBB COMPANY (US) 1998-09-03 WO disclosed
EP-0535448-B1 Process and intermediates for the preparation of an antiviral agent containing a cyclobutyl group SQUIBB & SONS INC (US) 1996-06-26 EP disclosed
US-5525726-A Process for the preparation of an antiviral agent E. R. SQUIBB & SONS, INC. (US) 1996-06-11 US disclosed
US-5516903-A Process for preparing [IR-(1α,2β-3α)]-2-amino-9-[2,3-bis(hydroxymethyl)cyclobutyl]-1,9-dihydro-6H-purin-6-one E. R. SQUIBB & SONS, INC. (US) 1996-05-14 US disclosed
US-5412134-A Process for preparing diprotected 2,3-hydroxymethyl cyclobutanol E. R. SQUIBB & SONS, INC. (US) 1995-05-02 US disclosed
CN-1082025-A 2 of two protections, the preparation method of 3-methylol cyclobutanol SQUIBB & SONS INC (US) 1994-02-16 CN disclosed
EP-0572209-A2 Process for preparing diprotected 2,3-hydroxymethyl cyclobutanol E.R. SQUIBB & SONS, INC. (US) 1993-12-01 EP disclosed
US-5237095-A Process for the preparation of an antiviral agent E. R. SQUIBB & SONS, INC. (US) 1993-08-17 US disclosed
US-5237096-A Process for the preparation of an antiviral agent E. R. SQUIBB & SONS, INC. (US) 1993-08-17 US disclosed
US-5233086-A Intermediates for the preparation of an antiviral agent E. R. SQUIBB & SONS, INC. (US) 1993-08-03 US disclosed
US-5218142-A Process for the preparation of an antiviral agent E. R. SQUIBB & SONS, INC. (US) 1993-06-08 US disclosed
EP-0535448-A2 Process and intermediates for the preparation of an antiviral agent containing a cyclobutyl group E.R. SQUIBB & SONS, INC. (US) 1993-04-07 EP disclosed
US-5185463-A PROCESS FOR THE PREPARATION OF AN ANTIVIRAL AGENT E. R. SQUIBB & SONS, INC. (US) 1993-02-09 US disclosed