Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7694272 | 1.00 | TSHR (0.57) | TSHRTHRBALDH1A1HTTDNM1 | |
| SCHEMBL7698973 | 1.00 | TSHR (0.57) | TSHRTHRBALDH1A1HTTDNM1 | |
| SCHEMBL7696949 | 1.00 | TSHR (0.57) | TSHRTHRBALDH1A1HTTDNM1 | |
| SCHEMBL7702997 | 1.00 | TSHR (0.57) | TSHRTHRBALDH1A1HTTDNM1 | |
| SCHEMBL7694903 | 1.00 | TSHR (0.57) | TSHRTHRBALDH1A1HTTDNM1 | |
| SCHEMBL2727729 | 1.00 | TSHR (0.57) | TSHRTHRBALDH1A1HTTDNM1 | |
| SCHEMBL1040798 | 1.00 | TSHR (0.57) | TSHRTHRBALDH1A1HTTDNM1 | |
| SCHEMBL7696608 | 1.00 | TSHR (0.57) | TSHRTHRBALDH1A1HTTDNM1 | |
| SCHEMBL7700832 | 1.00 | TSHR (0.57) | TSHRTHRBALDH1A1HTTDNM1 | |
| SCHEMBL2818833 | 0.96 | TSHR (0.50) | TSHRTHRBALDH1A1HTTDNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6346569-B1 | DISPERSING FEED POLYSUCCINIMIDE WITH DISPERSANT, REACTING DISPERSED POLYSUCCINIMIDE WITH CROSS-LINKING AGENT | MITSUI CHEMICALS, INC. (JP) | 2002-02-12 | — | — | US | disclosed |
| US-6072024-A | Production process of cross-linked polyaspartic acid resin | MITSUI CHEMICALS, INC. (JP) | 2000-06-06 | — | — | US | disclosed |
| US-5986042-A | Cross-linked polymer | MITSUI CHEMICALS, INC. (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0866084-A2 | Production process of cross-linked polyaspartic acid resin | Mitsui Chemicals, Inc. (JP) | 1998-09-23 | — | — | EP | disclosed |
| EP-0856539-A1 | Cross-linked polymer | Mitsui Chemicals, Inc. (JP) | 1998-08-05 | — | — | EP | disclosed |