Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 10/20 | 0.47 |
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | VCP | P55072 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | HCK | P08631 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695781 | 0.90 | DYRK1A (0.56) | DYRK1AKDM4EMAPK1TSHRHTT | |
| SCHEMBL7699589 | 0.89 | DYRK1A (0.55) | DYRK1AKDM4EMAPK1TSHRHTT | |
| SCHEMBL7697867 | 0.88 | DYRK1A (0.54) | DYRK1AKDM4EMAPK1TSHRHTT | |
| SCHEMBL8990998 | 0.88 | LRRK2 (0.56) | DYRK1AKDM4EMAPK1TSHRHTT | |
| SCHEMBL8991102 | 0.88 | DYRK1A (0.56) | DYRK1AKDM4EMAPK1TSHRHTT | |
| SCHEMBL7701007 | 0.87 | DYRK1A (0.54) | DYRK1AKDM4EMAPK1TSHRHTT | |
| SCHEMBL7699827 | 0.87 | DYRK1A (0.54) | DYRK1AKDM4EMAPK1TSHRHTT | |
| SCHEMBL7701084 | 0.86 | DYRK1A (0.53) | DYRK1AKDM4EMAPK1TSHRHTT | |
| SCHEMBL7702638 | 0.85 | DYRK1A (0.51) | DYRK1AKDM4EMAPK1TSHRHTT | |
| SCHEMBL7705445 | 0.83 | DYRK1A (0.49) | DYRK1AKDM4EMAPK1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |