Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702749 | 1.00 | MAPT (0.37) | MAPTKMT2AALDH1A1HTTGAA | |
| SCHEMBL8488252 | 0.77 | SLC6A4 (0.35) | MAPTKMT2AALDH1A1HTTKDM4E | |
| SCHEMBL8488251 | 0.77 | SLC6A4 (0.35) | MAPTKMT2AALDH1A1HTTKDM4E | |
| SCHEMBL8491834 | 0.76 | KMT2A (0.39) | MAPTKMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL8491832 | 0.76 | KMT2A (0.39) | MAPTKMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL8388430 | 0.73 | MAPT (0.33) | MAPTALDH1A1TDP1 | |
| SCHEMBL8727304 | 0.72 | TSHR (0.35) | MAPTKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL9242367 | 0.72 | ABCG2 (0.32) | MAPTALDH1A1HTTPOLB | |
| SCHEMBL9242363 | 0.72 | ABCG2 (0.32) | MAPTALDH1A1HTTPOLB | |
| SCHEMBL8489163 | 0.71 | MEN1 (0.38) | MAPTKMT2AALDH1A1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588357-B1 | Isoxazoles derivatives and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-06-12 | — | — | EP | disclosed |
| EP-1156048-A1 | Heteroaroyl-isoxazoles and their use as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 2001-11-21 | — | — | EP | disclosed |
| US-5480857-A | Herbicidal 4-heteroaroylisoxazole derivatives | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1996-01-02 | — | — | US | disclosed |
| EP-0588357-A1 | Isoxazoles derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-03-23 | — | — | EP | disclosed |