Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.58 |
| ▸ | PGR | P06401 | 9/20 | 0.51 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.46 |
| ▸ | SHBG | P04278 | 2/20 | 0.44 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702783 | 1.00 | AR (0.58) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL6464713 | 1.00 | AR (0.58) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL6466919 | 0.82 | AR (0.59) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL6466916 | 0.82 | AR (0.59) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL7698728 | 0.81 | AR (0.58) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL7700529 | 0.81 | AR (0.58) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL7700526 | 0.81 | AR (0.58) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL7880069 | 0.81 | AR (0.58) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL7698731 | 0.81 | AR (0.58) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL13334538 | 0.80 | AR (0.56) | ARPGRNR3C2SHBGSERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1163259-B1 | 14.BETA.,17-ALPHA-HYDROXYMETHYLANDROSTANE DERIVATIVES AS ANDROGENS | AKZO NOBEL NV (NL) | 2002-11-20 | — | — | EP | disclosed |