Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 11/20 | 0.54 |
| ▸ | NPY1R | P25929 | 6/20 | 0.54 |
| ▸ | NPY2R | P49146 | 4/20 | 0.54 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 3/20 | 0.45 |
| ▸ | FNTB | P49356 | 3/20 | 0.45 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.45 |
| ▸ | BACE1 | P56817 | 2/20 | 0.45 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31412176 | 0.93 | NPY4R (0.54) | NPY4RNPY1RNPY2RNPY5RFNTA | |
| SCHEMBL31345750 | 0.92 | NPY4R (0.64) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL29493332 | 0.92 | NPY4R (0.58) | NPY4RNPY1RNPY2RNPY5RKEAP1 | |
| SCHEMBL29540098 | 0.92 | NPY4R (0.49) | NPY4RNPY1RNPY2RNPY5RFNTA | |
| SCHEMBL31415960 | 0.91 | NPY4R (0.58) | NPY4RNPY1RNPY2RNPY5RBACE1 | |
| SCHEMBL29531710 | 0.91 | NPY4R (0.56) | NPY4RNPY1RNPY2RNPY5RFNTA | |
| SCHEMBL1737578 | 0.91 | NPY4R (0.56) | NPY4RNPY1RNPY2RNPY5RFNTA | |
| SCHEMBL1737572 | 0.91 | NPY4R (0.56) | NPY4RNPY1RNPY2RNPY5RFNTA | |
| SCHEMBL31184436 | 0.91 | NPY4R (0.56) | NPY4RNPY1RNPY2RNPY5RFNTA | |
| SCHEMBL30903451 | 0.90 | NPY4R (0.53) | NPY4RNPY1RNPY2RNPY5RKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1223215-A1 | TRANSFORMANT PRODUCING SECONDARY METABOLITE MODIFIED WITH FUNCTIONAL GROUP AND NOVEL BIOSYNTHESIS GENES | MEIJI SEIKA KAISHA LTD. (JP) | 2002-07-17 | — | — | EP | disclosed |
| EP-0081122-B1 | CARRIER TRIPEPTIDES WITH ANTIFUNGAL ACTIVITY | Helopharm W. Petrik GmbH & Co.KG. (DE) | 1985-10-02 | — | — | EP | disclosed |
| EP-0081122-A1 | Carrier tripeptides with antifungal activity | Helopharm W. Petrik GmbH & Co.KG. (DE) | 1983-06-15 | — | — | EP | disclosed |