Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 7/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL950663 | 0.86 | ELANE (0.55) | NPC1RAB9AELANECASP1F2 | |
| SCHEMBL7027446 | 0.83 | ELANE (0.55) | NPC1RAB9AELANECASP1F2 | |
| SCHEMBL6852036 | 0.83 | ELANE (0.54) | NPC1RAB9AELANECASP1F2 | |
| SCHEMBL12273254 | 0.81 | NPC1 (0.53) | NPC1RAB9AELANECASP1KMT2A | |
| SCHEMBL4902533 | 0.81 | NPC1 (0.53) | NPC1RAB9AELANECASP1KMT2A | |
| SCHEMBL8642645 | 0.80 | NPC1 (0.60) | NPC1RAB9AELANECASP1F2 | |
| SCHEMBL2798490 | 0.77 | ELANE (0.64) | NPC1RAB9AELANECASP1F2 | |
| SCHEMBL7322304 | 0.76 | NPC1 (0.55) | NPC1RAB9AELANECASP1F2 | |
| SCHEMBL948869 | 0.76 | ELANE (0.56) | NPC1RAB9AELANECASP1L3MBTL1 | |
| SCHEMBL8842031 | 0.75 | ELANE (0.49) | NPC1RAB9AELANECTRCSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342504-B1 | PEPTIDES AS ANTITHROMBINS AND ANTICOAGULANTS | CORVAS INTERNATIONAL, INC. | 2002-01-29 | — | — | US | disclosed |
| US-5656645-A | INHIBITORS OF THROMBIN | CORVAS INTERNATIONAL, INC. (US) | 1997-08-12 | — | — | US | disclosed |