Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 11/20 | 0.51 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703567 | 0.85 | HRH3 (0.55) | HRH3CYP19A1CPA1LOXL2 | |
| Hydrochloric Acid SCHEMBL7474426 | 0.84 | HRH3 (0.54) | HRH3CYP19A1CPA1 | |
| SCHEMBL7053727 | 0.79 | CPA1 (0.71) | HRH3CYP19A1CPA1 | |
| Hydrochloric Acid SCHEMBL8495732 | 0.78 | CPA1 (0.69) | HRH3CYP19A1CPA1 | |
| SCHEMBL7658759 | 0.76 | HRH3 (0.46) | HRH3CYP19A1CPA1 | |
| SCHEMBL7134263 | 0.76 | HRH3 (0.46) | HRH3CYP19A1 | |
| Hydrochloric Acid SCHEMBL7484921 | 0.75 | HRH3 (0.45) | HRH3CYP19A1 | |
| SCHEMBL7086614 | 0.75 | CPA1 (0.51) | HRH3CYP19A1CPA1 | |
| SCHEMBL7468703 | 0.73 | HRH3 (0.73) | HRH3CYP19A1 | |
| SCHEMBL7462978 | 0.73 | HRH3 (0.42) | HRH3CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002057223-A2 | COMPOUNDS AZEPANE, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS | LES LABORATOIRES SERVIER (FR) | 2002-07-25 | — | — | WO | claimed |