Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 8/20 | 0.67 |
| ▸ | EPHA2 | P29317 | 3/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.67 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.67 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.67 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.67 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.67 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.67 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.67 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.67 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | INPP5D | Q92835 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22404559 | 0.89 | GPBAR1 (0.72) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL18576355 | 0.89 | GPBAR1 (0.72) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL27625002 | 0.89 | GPBAR1 (0.72) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL7149599 | 0.89 | GPBAR1 (0.72) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL13139175 | 0.89 | GPBAR1 (0.72) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL15785703 | 0.89 | GPBAR1 (0.72) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL29602975 | 0.88 | GPBAR1 (0.64) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| Formic Acid SCHEMBL30422628 | 0.88 | GPBAR1 (0.64) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL30603073 | 0.86 | GPBAR1 (0.64) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL16881860 | 0.86 | GPBAR1 (0.46) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984980-B1 | 20-ARALKYL-5ALPHA-PREGNANE DERIVATIVES | AKZO NOBEL NV (NL) | 2002-12-04 | — | — | EP | disclosed |
| US-6177420-B1 | FERTILITY CONTROL AGENTS; SIDE EFFECT REDUCTION | AKZO NOBEL N.V. (NL) | 2001-01-23 | — | — | US | disclosed |
| EP-0984980-A1 | 20-ARALKYL-5$g(a)-PREGNANE DERIVATIVES | Akzo Nobel N.V. (NL) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998052965-A1 | 20-ARALKYL-5α-PREGNANE DERIVATIVES | AKZO NOBEL N.V. (NL) | 1998-11-26 | — | — | WO | disclosed |