Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 11/20 | 0.52 |
| ▸ | HTR3A | P46098 | 4/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6882169 | 0.92 | CHRNA7 (0.60) | CHRNA7HTR3AHTR3EHTR3BALOX15 | |
| SCHEMBL6884886 | 0.92 | CHRNA7 (0.60) | CHRNA7HTR3AHTR3EHTR3BALOX15 | |
| SCHEMBL6873808 | 0.81 | CHRNA7 (0.61) | CHRNA7HTR3AHTR3EHTR3BALOX15 | |
| SCHEMBL6881016 | 0.81 | CHRNA7 (0.63) | CHRNA7HTR3AHTR3EHTR3BALOX15 | |
| SCHEMBL6882107 | 0.80 | CHRNA7 (0.60) | CHRNA7HTR3AHTR3EHTR3BALOX15 | |
| SCHEMBL6878880 | 0.80 | CHRNA7 (0.62) | CHRNA7HTR3AHTR3EHTR3BALOX15 | |
| SCHEMBL6880483 | 0.79 | CHRNA7 (0.59) | CHRNA7HTR3AHTR3EHTR3BALOX15 | |
| SCHEMBL6883601 | 0.79 | CHRNA7 (0.63) | CHRNA7HTR3AHTR3EHTR3BALOX15 | |
| SCHEMBL6881596 | 0.78 | CHRNA7 (0.60) | CHRNA7HTR3AHTR3EHTR3BALOX15 | |
| SCHEMBL6880402 | 0.78 | CHRNA7 (0.64) | CHRNA7HTR3AHTR3EHTR3BALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002016357-A2 | QUINUCLIDINE-SUBSTITUTED ARYL MOIETIES FOR TREATMENT OF DISEASE (NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS) | PHARMACIA & UPJOHN COMPANY (US) | 2002-02-28 | — | — | WO | claimed |