Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.32 |
| ▸ | CBX7 | O95931 | 1/20 | 0.32 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.32 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701839 | 0.85 | ABCG2 (0.32) | MAPTALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL2846009 | 0.82 | PRMT1 (0.49) | MAPTALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL2846007 | 0.82 | PRMT1 (0.49) | MAPTALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL14769841 | 0.80 | MEN1 (0.36) | MAPTALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL14769832 | 0.79 | MAPT (0.48) | MAPTALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL16319609 | 0.79 | MAPT (0.48) | MAPTALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL13651942 | 0.77 | HTT (0.43) | MAPTALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL12156973 | 0.77 | PRMT1 (0.44) | MAPTALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL13657867 | 0.75 | PRMT1 (0.40) | MAPTALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL12156970 | 0.73 | MAPT (0.47) | MAPTALDH1A1NPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165693-A2 | SQUARAINE DYES | Amersham Pharmacia Biotech UK Limited (GB) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000058405-A2 | SQUARAINE DYES | AMERSHAM PHARMACIA BIOTECH UK LIMITED (GB) | 2000-10-05 | — | — | WO | disclosed |