Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1928712 | 0.98 | CYP19A1 (0.46) | CYP19A1CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL15314126 | 0.98 | CYP19A1 (0.46) | CYP19A1CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL13050136 | 0.98 | CYP19A1 (0.46) | CYP19A1CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL18596841 | 0.98 | CYP19A1 (0.46) | CYP19A1CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL10683938 | 0.96 | CYP19A1 (0.45) | CYP19A1CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL12165127 | 0.96 | CYP19A1 (0.45) | CYP19A1CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL12165121 | 0.93 | CHRM2 (0.47) | CYP19A1CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL12362878 | 0.93 | CHRM2 (0.47) | CYP19A1CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL14962378 | 0.93 | CHRM2 (0.47) | CYP19A1CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL7926056 | 0.84 | CHRM2 (0.48) | CHRM2CHRM1CHRM4CHRM3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6361940-B1 | IMMOBILIZATION; GENETIC ENGINEERING | QIAGEN GENOMICS, INC. | 2002-03-26 | — | — | US | disclosed |