Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.74 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6378266 | 0.93 | PARP1 (1.00) | PARP1 | |
| Hydrochloric Acid SCHEMBL6790211 | 0.92 | PARP1 (0.98) | PARP1 | |
| SCHEMBL6791769 | 0.90 | PARP1 (1.00) | PARP1 | |
| SCHEMBL6796664 | 0.89 | PARP1 (0.84) | PARP1 | |
| SCHEMBL6374166 | 0.86 | PARP1 (0.75) | PARP1KCNH2PARP2 | |
| SCHEMBL30249471 | 0.85 | PARP1 (1.00) | PARP1KCNH2PARP2 | |
| SCHEMBL6797445 | 0.85 | PARP1 (1.00) | PARP1KCNH2PARP2 | |
| SCHEMBL4316464 | 0.85 | PARP1 (1.00) | PARP1KCNH2PARP2 | |
| SCHEMBL29903051 | 0.81 | PARP1 (1.00) | PARP1PARP2 | |
| SCHEMBL20339795 | 0.81 | PARP1 (1.00) | PARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130116284-A1 | LIPOIC ACID AND NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2013-05-09 | — | — | US | disclosed |
| US-20130116284-A1 | LIPOIC ACID AND NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2013-05-09 | — | — | US | disclosed |
| WO-2011141909-A2 | LIPOIC ACID AND NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2011-11-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130116284-A1 | LIPOIC ACID AND NITROXIDE DERIVATIVES AND USES THEREOF | PARP1, PARP2, PARP6 | PARP1 1/4885KCNH2 4841/4885PARP2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.