Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | NPC1 | O15118 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | NR2F2 | P24468 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | RAB9A | P51151 | 1/20 | 1.00 |
| ▸ | RUNX1 | Q01196 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | CBFB | Q13951 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | FURIN | P09958 | 1/20 | 0.97 |
| ▸ | INMT | O95050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL7704714 | 1.00 | KDM4E (1.00) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL13416790 | 0.99 | FURIN (1.00) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL10035972 | 0.99 | FURIN (1.00) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL12611377 | 0.99 | FURIN (1.00) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL14594151 | 0.83 | FURIN (0.73) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL14116777 | 0.81 | FURIN (0.70) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL13416789 | 0.81 | FURIN (0.70) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL14465590 | 0.77 | FURIN (0.64) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL13416820 | 0.75 | FURIN (0.61) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL13416564 | 0.74 | FURIN (0.60) | KDM4EMEN1NPC1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342329-B1 | Image-forming medium | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2002-01-29 | — | — | US | claimed |
| US-6342329-B1 | Image-forming medium | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2002-01-29 | — | — | US | disclosed |
| EP-0930539-A1 | Image-forming medium | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 1999-07-21 | — | — | EP | disclosed |