Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9041378 | 0.98 | CHRM2 (0.35) | CHRM2CHRM1CHRM3KCNH2SLC6A4 | |
| SCHEMBL15028241 | 0.83 | SLC6A4 (0.37) | CHRM2CHRM1CHRM3KCNH2SLC6A4 | |
| SCHEMBL18746525 | 0.67 | SLC6A4 (0.33) | KCNH2SLC6A4SLC6A3 | |
| SCHEMBL17966147 | 0.66 | KCNH2 (0.36) | KCNH2SLC6A4SLC6A3 | |
| SCHEMBL1096051 | 0.66 | KCNH2 (0.36) | KCNH2SLC6A4SLC6A3 | |
| SCHEMBL19799180 | 0.66 | KCNH2 (0.33) | KCNH2 | |
| SCHEMBL19799174 | 0.66 | KCNH2 (0.36) | KCNH2SLC6A4SLC6A3 | |
| SCHEMBL10610010 | 0.66 | KCNH2 (0.36) | KCNH2SLC6A4SLC6A3 | |
| SCHEMBL22113003 | 0.66 | KCNH2 (0.33) | KCNH2 | |
| SCHEMBL10081289 | 0.66 | CHRM2 (0.42) | CHRM2CHRM1KCNH2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445731-B1 | Azabicyclo and azacyclo oxime and amine cholinergic agents and pharmaceutically acceptable salts thereof | WARNER LAMBERT CO (US) | 1996-01-10 | — | — | EP | claimed |
| EP-1211940-A1 | AZABICYCLO AND AZACYCLO OXIME AND AMINE COMPOUNDS AS PESTICIDES | Aventis CropScience GmbH (DE) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001015532-A1 | AZABICYCLO AND AZACYCLO OXIME AND AMINE COMPOUNDS AS PESTICIDES | AVENTIS CROPSCIENCE GMBH (DE) | 2001-03-08 | — | — | WO | disclosed |