Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699960 | 0.91 | IKBKB (0.44) | IKBKBMAPTRXFP1HDAC6HDAC3 | |
| SCHEMBL7699558 | 0.89 | IKBKB (0.42) | IKBKBMAPTRXFP1ALDH1A1HSD17B10 | |
| SCHEMBL7700110 | 0.88 | KDM4E (0.44) | IKBKBMAPTRXFP1ALDH1A1HSD17B10 | |
| SCHEMBL7701990 | 0.85 | IKBKB (0.46) | IKBKBMAPTRXFP1ALDH1A1HDAC6 | |
| SCHEMBL7693990 | 0.83 | IKBKB (0.53) | IKBKBMAPTRXFP1ALDH1A1HSD17B10 | |
| SCHEMBL7701275 | 0.82 | IKBKB (0.63) | IKBKBMAPTRXFP1ALDH1A1HSD17B10 | |
| SCHEMBL7699217 | 0.80 | MAPT (0.36) | MAPTRXFP1ALDH1A1HSD17B10TSHR | |
| SCHEMBL7699727 | 0.79 | IKBKB (0.42) | IKBKBMAPTCNR2ALDH1A1TSHR | |
| SCHEMBL7700016 | 0.78 | IKBKB (0.42) | IKBKBMAPTRXFP1TSHRHPGD | |
| SCHEMBL7699330 | 0.77 | KDM4E (0.53) | IKBKBMAPTALDH1A1HSD17B10NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |