Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 5/20 | 0.45 |
| ▸ | CTSD | P07339 | 4/20 | 0.45 |
| ▸ | FNTA | P49354 | 8/20 | 0.44 |
| ▸ | FNTB | P49356 | 8/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 2/20 | 0.40 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7705051 | 1.00 | BACE1 (0.45) | BACE1CTSDFNTAFNTBFOLH1 | |
| SCHEMBL29886740 | 0.88 | MME (0.45) | BACE1CTSDFNTAFNTBMME | |
| SCHEMBL29776104 | 0.86 | CYP2C9 (0.41) | BACE1FNTAFNTB | |
| SCHEMBL9561613 | 0.85 | FOLH1 (0.53) | BACE1CTSDFNTAFNTBFOLH1 | |
| SCHEMBL9561619 | 0.85 | FOLH1 (0.53) | BACE1CTSDFNTAFNTBFOLH1 | |
| SCHEMBL29350681 | 0.85 | FOLH1 (0.53) | BACE1CTSDFNTAFNTBFOLH1 | |
| SCHEMBL29445196 | 0.83 | BACE1 (0.46) | BACE1CTSDFNTAFNTBBACE2 | |
| SCHEMBL31341165 | 0.83 | BACE1 (0.46) | BACE1CTSDBACE2 | |
| SCHEMBL30052377 | 0.82 | FNTA (0.48) | FNTAFNTB | |
| SCHEMBL30052430 | 0.82 | FNTA (0.43) | BACE1CTSDFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6359113-B1 | USING FUSED RING SYSTEM CONTAINING AT LEAST 4 AROMATIC RINGS, AND GROUP CONTAINING AT LEAST ONE CARBON ATOM WHICH IS CAPABLE OF BONDING TO A GROUP TO BE PROTECTED; SYNTHESIS, SEPARATION | RHODIA CHIMIE (FR) | 2002-03-19 | — | — | US | disclosed |
| EP-0565607-B1 | PROTECTION GROUP, COMPOUD PROTECTED BY THIS GROUP AND DEVICE FOR GRAFTING THE PROTECTION GROUP ONTO THE COMPOUND BEING PROTECTED | RHODIA CHIMIE SA (FR) | 1999-04-21 | — | — | EP | disclosed |
| US-5869605-A | Protected compound comprising a protective group removably attached to a compound to be protected | RHONE-POULENCCHIMIE (FR) | 1999-02-09 | — | — | US | disclosed |