Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700036 | 0.93 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1SLC22A1ALDH1A1DHFR | |
| SCHEMBL7705625 | 0.93 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1SLC22A1ALDH1A1DHFR | |
| SCHEMBL7699134 | 0.93 | MEN1 (0.45) | SMN1; SMN2MEN1SLC22A1ALDH1A1DHFR | |
| SCHEMBL7698069 | 0.93 | MEN1 (0.45) | SMN1; SMN2MEN1SLC22A1ALDH1A1DHFR | |
| SCHEMBL7705940 | 0.90 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1SLC22A1ALDH1A1DHFR | |
| SCHEMBL7699850 | 0.90 | SMN1; SMN2 (0.43) | SMN1; SMN2MEN1SLC22A1ALDH1A1DHFR | |
| SCHEMBL7704122 | 0.87 | MEN1 (0.44) | SMN1; SMN2MEN1SLC22A1ALDH1A1DHFR | |
| SCHEMBL7703611 | 0.87 | — | — | |
| SCHEMBL7703562 | 0.86 | MEN1 (0.43) | SMN1; SMN2MEN1SLC22A1ALDH1A1DHFR | |
| SCHEMBL7702899 | 0.86 | SMN1; SMN2 (0.43) | SMN1; SMN2MEN1SLC22A1ALDH1A1DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901488-B1 | 2,4-DIAMINOPYRIMIDINE DERIVATIVES | BASILEA PHARMACEUTICA AG (CH) | 2002-11-06 | — | — | EP | disclosed |