Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.89 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29359902 | 0.94 | BTK (1.00) | BTK | |
| SCHEMBL769731 | 0.94 | BTK (1.00) | BTK | |
| SCHEMBL1067909 | 0.91 | BTK (0.94) | BTK | |
| SCHEMBL26970141 | 0.91 | BTK (0.74) | BTK | |
| SCHEMBL1069710 | 0.91 | BTK (0.88) | BTK | |
| SCHEMBL1067840 | 0.91 | BTK (1.00) | BTK | |
| SCHEMBL1067061 | 0.89 | BTK (1.00) | BTK | |
| SCHEMBL770762 | 0.89 | BTK (1.00) | BTK | |
| SCHEMBL1069586 | 0.89 | BTK (0.87) | BTK | |
| SCHEMBL1069889 | 0.89 | BTK (0.86) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260014157-A1 | USE OF INHIBITORS OF BRUTONS TYROSINE KINASE (BTK) | PHARMACYCLICS LLC (US) | 2026-01-15 | — | — | US | disclosed |
| US-20250127781-A1 | USE OF INHIBITORS OF BRUTON'S TYROSINE KINASE (BTK) | PHARMACYCLICS, INC. | 2025-04-24 | — | — | US | disclosed |
| US-20240065971-A1 | METHODS OF TREATING ABC-DLBCL USING INHIBITORS OF BRUTONS TYROSINE KINASE | PHARMACYCLICS LLC (US) | 2024-02-29 | — | — | US | disclosed |
| US-20230293532-A1 | USE OF INHIBITORS OF BRUTONS TYROSINE KINASE (BTK) | PHARMACYCLICS LLC (US) | 2023-09-21 | — | — | US | disclosed |
| US-20230248730-A1 | USE OF INHIBITORS OF BRUTONS TYROSINE KINASE (BTK) | PHARMACYCLICS LLC (US) | 2023-08-10 | — | — | US | disclosed |
| US-11672803-B2 | Use of inhibitors of Brutons tyrosine kinase (Btk) | PHARMACYCLICS LLC (US) | 2023-06-13 | — | — | US | disclosed |
| US-20220249494-A1 | USE OF INHIBITORS OF BRUTONS TYROSINE KINASE (BTK) | PHARMACYCLICS LLC (US) | 2022-08-11 | — | — | US | disclosed |
| US-20220175785-A1 | USE OF INHIBITORS OF BRUTONS TYROSINE KINASE (BTK) | PHARMACYCLICS LLC (US) | 2022-06-09 | — | — | US | disclosed |
| US-20210361657-A1 | USE OF INHIBITORS OF BRUTONS TYROSINE KINASE (BTK) | PHARMACYCLICS LLC (US) | 2021-11-25 | — | — | US | disclosed |
| US-20210169885-A1 | USE OF INHIBITORS OF BRUTONS TYROSINE KINASE (BTK) | PHARMACYCLICS LLC | 2021-06-10 | — | — | US | disclosed |
| US-20130195852-A1 | USE OF INHIBITORS OF BRUTON'S TYROSINE KINASE (BTK) | PHARMACYCLICS, INC. (US) | 2013-08-01 | — | — | US | disclosed |
| US-20130178483-A1 | Methods and Compositions for Inhibition of Bone Resorption | PHARMACYCLICS, INC. (US) | 2013-07-11 | — | — | US | disclosed |
| WO-2013059738-A2 | USE OF INHIBITORS OF BRUTON'S TYROSINE KINASE (BTK) | PHARMACYCLICS, INC. (US) | 2013-04-25 | — | — | WO | disclosed |
| EP-2575818-A2 | THE USE OF INHIBITORS OF BRUTON'S TYROSINE KINASE (BTK) | Pharmacyclics, Inc. (US) | 2013-04-10 | — | — | EP | disclosed |
| WO-2013003629-A2 | METHODS AND COMPOSITIONS FOR INHIBITION OF BONE RESORPTION | PHARMACYCLICS, INC. (US) | 2013-01-03 | — | — | WO | disclosed |
| US-20120183535-A1 | USE OF INHIBITORS OF BRUTON'S TYROSINE KINASE (BTK) | PHARMACYCLICS, INC. (US) | 2012-07-19 | — | — | US | disclosed |
| US-20120100138-A1 | THE USE OF INHIBITORS OF BRUTON'S TYROSINE KINASE (BTK) | PHARMACYCLICS, INC. (US) | 2012-04-26 | — | — | US | disclosed |
| US-20120087915-A1 | USE OF INHIBITORS OF BRUTON'S TYROSINE KINASE (BTK) | PHARMACYCLICS, INC. (US) | 2012-04-12 | — | — | US | disclosed |
| US-20120071497-A1 | METHODS OF TREATING ABC-DLBCL USING INHIBITORS OF BRUTON'S TYROSINE KINASE | PHARMACYCLICS, INC. (US) | 2012-03-22 | — | — | US | disclosed |
| WO-2011153514-A2 | THE USE OF INHIBITORS OF BRUTON'S TYROSINE KINASE (BTK) | PHARMACYCLICS, INC. (US) | 2011-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (16 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210169885-A1 | USE OF INHIBITORS OF BRUTONS TYROSINE KINASE (BTK) | BTK, LYN, SYK | BTK 1/4885 |
| US-20210361657-A1 | USE OF INHIBITORS OF BRUTONS TYROSINE KINASE (BTK) | BTK, LYN, SYK | BTK 1/4885 |
| US-20120071497-A1 | METHODS OF TREATING ABC-DLBCL USING INHIBITORS OF BRUTON'S TYROSINE KINASE | BTK, BCL6, BCL6B | BTK 1/4885 |
| US-20260014157-A1 | USE OF INHIBITORS OF BRUTONS TYROSINE KINASE (BTK) | BTK, BCL6B, BCL9 | BTK 1/4885 |
| US-20130195852-A1 | USE OF INHIBITORS OF BRUTON'S TYROSINE KINASE (BTK) | BTK, SYK, LYN | BTK 1/4885 |
| US-20240065971-A1 | METHODS OF TREATING ABC-DLBCL USING INHIBITORS OF BRUTONS TYROSINE KINASE | BTK, BCL6, BCL6B | BTK 1/4885 |
| US-20220249494-A1 | USE OF INHIBITORS OF BRUTONS TYROSINE KINASE (BTK) | BTK, LYN, SYK | BTK 1/4885 |
| US-20130178483-A1 | Methods and Compositions for Inhibition of Bone Resorption | BTK, CTTN, BMX | BTK 1/4885 |
| US-20230248730-A1 | USE OF INHIBITORS OF BRUTONS TYROSINE KINASE (BTK) | BTK, LYN, SYK | BTK 1/4885 |
| US-11672803-B2 | Use of inhibitors of Brutons tyrosine kinase (Btk) | BTK, LYN, SYK | BTK 1/4885 |
| US-20250127781-A1 | USE OF INHIBITORS OF BRUTON'S TYROSINE KINASE (BTK) | BTK, LYN, SYK | BTK 1/4885 |
| US-20230293532-A1 | USE OF INHIBITORS OF BRUTONS TYROSINE KINASE (BTK) | BTK, LYN, SYK | BTK 1/4885 |
| US-20220175785-A1 | USE OF INHIBITORS OF BRUTONS TYROSINE KINASE (BTK) | BTK, LYN, SYK | BTK 1/4885 |
| US-20120087915-A1 | USE OF INHIBITORS OF BRUTON'S TYROSINE KINASE (BTK) | BTK, SYK, LYN | BTK 1/4885 |
| US-20120183535-A1 | USE OF INHIBITORS OF BRUTON'S TYROSINE KINASE (BTK) | BTK, SYK, LYN | BTK 1/4885 |
| US-20120100138-A1 | THE USE OF INHIBITORS OF BRUTON'S TYROSINE KINASE (BTK) | BTK, SYK, LYN | BTK 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.