Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 6/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3066069 | 1.00 | PRCP (0.66) | PRCPGAARECQLGID4CHRNB2 | |
| SCHEMBL7699909 | 0.82 | PRCP (0.66) | PRCPGAARECQLGID4 | |
| SCHEMBL7699907 | 0.82 | PRCP (0.66) | PRCPGAARECQLGID4 | |
| SCHEMBL21063715 | 0.80 | PRCP (1.00) | PRCPGAARECQLGID4 | |
| SCHEMBL30973226 | 0.80 | PRCP (1.00) | PRCPGAARECQLGID4 | |
| SCHEMBL3072702 | 0.80 | PRCP (1.00) | PRCPGAARECQLGID4 | |
| SCHEMBL7702915 | 0.79 | PRCP (0.57) | PRCPGAARECQLGID4 | |
| SCHEMBL3063503 | 0.79 | PRCP (0.57) | PRCPGAARECQLGID4 | |
| SCHEMBL7698245 | 0.79 | PRCP (0.57) | PRCPGAARECQLGID4 | |
| SCHEMBL7702912 | 0.79 | PRCP (0.57) | PRCPGAARECQLGID4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901488-B1 | 2,4-DIAMINOPYRIMIDINE DERIVATIVES | BASILEA PHARMACEUTICA AG (CH) | 2002-11-06 | — | — | EP | disclosed |
| EP-0901488-A1 | 2,4-DIAMINOPYRIMIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-03-17 | — | — | EP | disclosed |
| US-5866583-A | Substituted 2,4-diaminopyrimidines | HOFFMANN-LA ROCHE INC. (US) | 1999-02-02 | — | — | US | disclosed |
| WO-1997043277-A1 | 2,4-DIAMINOPYRIMIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1997-11-20 | — | — | WO | disclosed |