Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | GAPDH | P04406 | 2/20 | 0.55 |
| ▸ | HRAS | P01112 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.42 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.41 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15095559 | 1.00 | POLB (0.59) | POLBMEN1USP2KMT2AGAPDH | |
| SCHEMBL9133790 | 0.94 | POLB (0.53) | POLBMEN1USP2KMT2AGAPDH | |
| SCHEMBL6765430 | 0.88 | MEN1 (0.59) | POLBMEN1USP2KMT2AGAPDH | |
| SCHEMBL8516844 | 0.88 | MEN1 (0.59) | POLBMEN1USP2KMT2AGAPDH | |
| SCHEMBL14011209 | 0.88 | MEN1 (0.59) | POLBMEN1USP2KMT2AGAPDH | |
| Hydrochloric Acid SCHEMBL11628090 | 0.87 | MEN1 (0.58) | POLBMEN1USP2KMT2AGAPDH | |
| SCHEMBL7706306 | 0.87 | POLB (0.58) | POLBMEN1USP2KMT2AGAPDH | |
| SCHEMBL23240641 | 0.86 | POLB (0.60) | POLBMEN1USP2KMT2AGAPDH | |
| SCHEMBL21586638 | 0.86 | POLB (0.60) | POLBMEN1USP2KMT2AGAPDH | |
| SCHEMBL17968547 | 0.86 | POLB (0.60) | POLBMEN1USP2KMT2AGAPDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369040-B1 | INCORPORATING A COMPLEMENTARY SEQUENCES FOR HERPES, PAPILLOMA AND OTHER VIRUSES | ISIS PHARMACEUTICALS, INC. | 2002-04-09 | — | — | US | disclosed |
| US-6060592-A | Pyrimidine nucleoside compounds and oligonucleoside compounds containing same | ISIS PHARMACEUTICALS, INC. (US) | 2000-05-09 | — | — | US | disclosed |