Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.53 |
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.53 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7712708 | 0.90 | GPBAR1 (0.50) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7704262 | 0.80 | GPBAR1 (0.50) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7712828 | 0.78 | PDE10A (0.48) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7710762 | 0.74 | NPC1 (0.34) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7705628 | 0.74 | GPBAR1 (0.49) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7703187 | 0.74 | GPBAR1 (0.63) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL1695576 | 0.74 | GPBAR1 (0.63) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL1695577 | 0.74 | GPBAR1 (0.63) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7707067 | 0.73 | GPBAR1 (0.53) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL1695698 | 0.73 | GPBAR1 (0.58) | CYSLTR1GPBAR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011138657-A1 | ARYL SUBSTITUTED OLEFINIC COMPOUNDS AS PDE10A INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2011-11-10 | — | — | WO | disclosed |