Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 17/20 | 0.85 |
| ▸ | HTR2A | P28223 | 1/20 | 0.65 |
| ▸ | HTR2C | P28335 | 1/20 | 0.65 |
| ▸ | HTR2B | P41595 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6780173 | 0.92 | HRH2 (1.00) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL6781533 | 0.91 | HRH2 (1.00) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL6776305 | 0.88 | HRH2 (1.00) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL4055187 | 0.86 | HRH2 (0.80) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL6781106 | 0.84 | HRH2 (0.93) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL6776622 | 0.83 | HRH2 (0.84) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL6778661 | 0.83 | HRH2 (1.00) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL6781750 | 0.83 | HRH2 (1.00) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL6780899 | 0.82 | HRH2 (0.84) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL6778775 | 0.82 | HRH2 (0.88) | HRH2HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183251-A1 | INDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | Almirall Prodesfarma, S.A. (ES) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000075130-A1 | INDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | ALMIRALL PRODESFARMA, S.A. (ES) | 2000-12-14 | — | — | WO | disclosed |