Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 13/20 | 0.52 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.52 |
| ▸ | HTR3B | O95264 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTR3A | P46098 | 1/20 | 0.52 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.52 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6883948 | 1.00 | CHRNA7 (0.52) | CHRNA7HTR3EHTR3BALOX15TSHR | |
| SCHEMBL6882027 | 0.92 | CHRNA7 (0.52) | CHRNA7HTR3EHTR3BALOX15TSHR | |
| SCHEMBL7597490 | 0.88 | CHRNA7 (0.61) | CHRNA7HTR3EHTR3BALOX15TSHR | |
| SCHEMBL6883916 | 0.86 | CHRNA7 (0.52) | CHRNA7HTR3EHTR3BALOX15TSHR | |
| SCHEMBL6874735 | 0.86 | CHRNA7 (0.61) | CHRNA7HTR3EHTR3BALOX15TSHR | |
| SCHEMBL7047279 | 0.85 | CHRNA7 (0.55) | CHRNA7HTR3EHTR3BALOX15TSHR | |
| SCHEMBL6883309 | 0.85 | CHRNA7 (0.57) | CHRNA7HTR3EHTR3BALOX15TSHR | |
| SCHEMBL6880936 | 0.85 | CHRNA7 (0.50) | CHRNA7HTR3EHTR3BALOX15TSHR | |
| SCHEMBL7059133 | 0.84 | CHRNA7 (0.55) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL6883512 | 0.84 | CHRNA7 (0.52) | CHRNA7HTR3EHTR3BALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002016357-A2 | QUINUCLIDINE-SUBSTITUTED ARYL MOIETIES FOR TREATMENT OF DISEASE (NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS) | PHARMACIA & UPJOHN COMPANY (US) | 2002-02-28 | — | — | WO | claimed |