Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 11/20 | 0.52 |
| ▸ | HTR3A | P46098 | 5/20 | 0.52 |
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.52 |
| ▸ | HTR3B | O95264 | 4/20 | 0.52 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.52 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6880991 | 1.00 | CHRNA7 (0.52) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL7704271 | 0.89 | CHRNA7 (0.46) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL6884610 | 0.88 | CHRNA7 (0.54) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL372989 | 0.88 | CHRNA7 (0.60) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL6879605 | 0.87 | CHRNA7 (0.55) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL6880994 | 0.87 | CHRNA7 (0.55) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL6874525 | 0.85 | CHRNA7 (0.64) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL6883595 | 0.84 | CHRNA7 (0.52) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL6880646 | 0.83 | CHRNA7 (0.65) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL6884756 | 0.83 | CHRNA7 (0.53) | CHRNA7HTR3AHTR3EHTR3BHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002016357-A2 | QUINUCLIDINE-SUBSTITUTED ARYL MOIETIES FOR TREATMENT OF DISEASE (NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS) | PHARMACIA & UPJOHN COMPANY (US) | 2002-02-28 | — | — | WO | claimed |