Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL7706882

CCCCCCCCCCCC(OCCC)S(=O)(=O)O.N

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.43
SMPD1 P17405 3/20 0.37
CA1 P00915 8/20 0.36
CA2 P00918 8/20 0.36
CA9 Q16790 7/20 0.36
GPR84 Q9NQS5 3/20 0.36
CA12 O43570 3/20 0.36
CA7 P43166 3/20 0.36
CA14 Q9ULX7 3/20 0.36
FDPS P14324 3/20 0.36
CA3 P07451 2/20 0.36
CA4 P22748 2/20 0.36
CA6 P23280 2/20 0.36
CA5A P35218 2/20 0.36
CA5B Q9Y2D0 2/20 0.36
FFAR1 O14842 1/20 0.36
ZDHHC7 Q9NXF8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3682679 0.98 TP53 (0.44) TP53SMPD1CA1CA2CA9
Ammonia Solution, Strong SCHEMBL29166538 0.93 TP53 (0.43) TP53SMPD1CA1CA2CA9
Ammonia Solution, Strong SCHEMBL29166217 0.93 TP53 (0.43) TP53SMPD1CA1CA2CA9
SCHEMBL28339881 0.91 TP53 (0.44) TP53SMPD1CA1CA2CA9
SCHEMBL1974092 0.91 TP53 (0.44) TP53SMPD1CA1CA2CA9
SCHEMBL28677795 0.85 TP53 (0.50) TP53SMPD1CA1CA2GPR84
SCHEMBL11759627 0.85 TP53 (0.41) TP53CA1CA2CA9CA12
SCHEMBL8740084 0.85 TP53 (0.50) TP53SMPD1CA1CA2GPR84
SCHEMBL9822598 0.84 CA1 (0.41) TP53CA1CA2CA9CA12
SCHEMBL15345889 0.83 HDAC1 (0.37) TP53CA1CA2CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6361768-B1 POLYMER FORMED BY COPOLYMERIZATION OF ANIONIC MONOMER HAVING CARBOXY-FUNCTIONAL GROUP, NON-QUATERNIZED CATIONIC MONOMER HAVING AMINO-FUNCTIONAL GROUP, NON-IONIC HYDROPHILIC MONOMER, HYDROPHOBIC MONOMER, OPTIONAL CROSSLINKING MONOMER PMD HOLDINGS CORP. 2002-03-26 US disclosed
EP-1147138-A1 HYDROPHILIC AMPHOLYTIC POLYMER The B.F. Goodrich Company (US) 2001-10-24 EP disclosed
WO-2000039176-A1 HYDROPHILIC AMPHOLYTIC POLYMER THE B.F. GOODRICH COMPANY (US) 2000-07-06 WO disclosed
US-5393452-A Improved antistatic properties GENERAL ELECTRIC COMPANY (US) 1995-02-28 US disclosed
EP-0598531-A2 2 in 1 shampoo and conditioner comprising a silicone-polyether copolymer GENERAL ELECTRIC COMPANY (US) 1994-05-25 EP disclosed
EP-0581442-A2 Shampoo composition GENERAL ELECTRIC COMPANY (US) 1994-02-02 EP disclosed
US-5151210-A Lotions of synthetic surfactants, selenium sulfide and nonionic polymers THE PROCTER & GAMBLE COMPANY (US) 1992-09-29 US disclosed
EP-0208533-B1 SHAMPOO COMPOSITIONS AND USE THEREOF THE PROCTER & GAMBLE COMPANY (US) 1991-04-10 EP disclosed
EP-0190010-B1 SHAMPOO COMPOSITIONS AND METHOD THE PROCTER & GAMBLE COMPANY (US) 1991-04-10 EP disclosed
US-4824602-A WASHING WITH ACETONITRILE, ACETONE OR DIETHYL ETHER, DRYING; FOR SHAMPOOS OR HAIR CONDITIONERS THE PROCTER & GAMBLE COMPANY (US) 1989-04-25 US disclosed
US-4704272-A HAIR CONDITIONERS THE PROCTER & GAMBLE COMPANY (US) 1987-11-03 US disclosed
EP-0208533-A2 Shampoo compositions and use thereof THE PROCTER & GAMBLE COMPANY (US) 1987-01-14 EP disclosed
EP-0190010-A2 Shampoo compositions and method THE PROCTER & GAMBLE COMPANY (US) 1986-08-06 EP disclosed