Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2631088 | 0.88 | PDE10A (0.67) | PDE10A | |
| SCHEMBL2631055 | 0.88 | PDE10A (0.74) | PDE10A | |
| SCHEMBL7702792 | 0.86 | PDE10A (0.52) | PDE10A | |
| SCHEMBL2630897 | 0.86 | PDE10A (0.54) | PDE10A | |
| SCHEMBL7702442 | 0.81 | PDE10A (0.56) | PDE10A | |
| SCHEMBL2630868 | 0.80 | PDE10A (0.57) | PDE10A | |
| SCHEMBL7710364 | 0.78 | PDE10A (0.51) | PDE10A | |
| Hydrochloric Acid SCHEMBL15134978 | 0.77 | PDE10A (0.50) | PDE10A | |
| SCHEMBL7704653 | 0.77 | PDE10A (0.74) | PDE10A | |
| SCHEMBL2630808 | 0.76 | PDE10A (0.50) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011143495-A1 | HETEROARYLOXYHETEROCYCLYL COMPOUNDS AS PDE10 INHIBITORS | AMGEN INC. (US) | 2011-11-17 | — | — | WO | disclosed |