Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7710773 | 1.00 | CHRM5 (0.42) | CHRM5CHRM3SIGMAR1SMN1; SMN2HSD17B10 | |
| SCHEMBL7708046 | 1.00 | CHRM5 (0.42) | CHRM5CHRM3SIGMAR1SMN1; SMN2HSD17B10 | |
| SCHEMBL7228712 | 0.89 | CHRM5 (0.46) | CHRM5CHRM3SIGMAR1SMN1; SMN2HSD17B10 | |
| SCHEMBL7710764 | 0.88 | CHRM5 (0.33) | CHRM5CHRM3SIGMAR1 | |
| SCHEMBL7708083 | 0.88 | CHRM5 (0.33) | CHRM5CHRM3SIGMAR1 | |
| SCHEMBL7708079 | 0.88 | CHRM5 (0.33) | CHRM5CHRM3SIGMAR1 | |
| SCHEMBL18995439 | 0.84 | CHRM5 (0.40) | CHRM5CHRM3SIGMAR1SMN1; SMN2HSD17B10 | |
| SCHEMBL15100753 | 0.83 | CHRM5 (0.37) | CHRM5CHRM3SIGMAR1 | |
| SCHEMBL7221597 | 0.83 | CHRM5 (0.46) | CHRM5CHRM3SIGMAR1SMN1; SMN2HSD17B10 | |
| SCHEMBL7221599 | 0.83 | CHRM5 (0.46) | CHRM5CHRM3SIGMAR1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6359174-B1 | REACTING ALLYL REACTANT WITH ACID CHLORIDE IN PRESENCE OF LEWIS ACID CATALYST | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-03-19 | — | — | US | disclosed |
| US-4353826-A | ANTITUBERCULAR ANTIBIOTICS | CIBA-GEIGY CORPORATION (US) | 1982-10-12 | — | — | US | disclosed |
| EP-0049683-A2 | Imidazo-rifamycines, process for their preparation, pharmaceutical preparations containing them and their use | CIBA-GEIGY AG (CH) | 1982-04-14 | — | — | EP | disclosed |
| US-4261891-A | BACTERICIDES, ANTITUBERCULAR AGENTS | CIBA-GEIGY CORPORATION (US) | 1981-04-14 | — | — | US | disclosed |
| US-4005077-A | DERIVATIVES OF RIFAMYCIN S OR SV | CIBA-GEIGY CORPORATION (US) | 1977-01-25 | — | — | US | disclosed |