Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 6/20 | 0.41 |
| ▸ | TYMP | P19971 | 2/20 | 0.38 |
| ▸ | TK2 | O00142 | 2/20 | 0.38 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.37 |
| ▸ | TK1 | P04183 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7708172 | 1.00 | TOP2A (0.41) | TOP2ATYMPTK2RNASE1TK1 | |
| SCHEMBL10647357 | 0.84 | TK2 (0.45) | TOP2ATYMPTK2RNASE1TK1 | |
| SCHEMBL10643570 | 0.84 | TK2 (0.45) | TOP2ATYMPTK2RNASE1TK1 | |
| SCHEMBL1738199 | 0.84 | TOP2A (0.38) | TOP2ATYMPTK2RNASE1TK1 | |
| SCHEMBL1738201 | 0.84 | TOP2A (0.38) | TOP2ATYMPTK2RNASE1TK1 | |
| SCHEMBL5668666 | 0.84 | P2RY2 (0.44) | TOP2A | |
| SCHEMBL6853095 | 0.83 | TYMP (0.39) | TOP2ATYMPTK2RNASE1TK1 | |
| SCHEMBL7065019 | 0.83 | TK2 (0.42) | TOP2ATYMPTK2TK1 | |
| SCHEMBL7065021 | 0.83 | TK2 (0.42) | TOP2ATYMPTK2TK1 | |
| SCHEMBL10646821 | 0.82 | TOP2A (0.41) | TOP2ATYMPTK2RNASE1TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6359124-B1 | NUCLEOTIDE SEQUENCES FOR USE IN THE DIAGNOSIS, DETECTION AND TREATMENT OF ARRHYTHMIA, LONG Q-T SYNDROME AND CANCERS | ISIS PHARMACEUTICALS, INC. | 2002-03-19 | — | — | US | disclosed |