Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL8815610 | 0.92 | TDP1 (0.53) | — | |
| Propylene Glycol SCHEMBL8832136 | 0.90 | — | — | |
| Propylene Glycol SCHEMBL27548540 | 0.88 | — | — | |
| Propylene Glycol SCHEMBL320017 | 0.87 | — | — | |
| Propylene Glycol SCHEMBL28574118 | 0.87 | TDP1 (0.71) | — | |
| Propylene Glycol SCHEMBL29352119 | 0.87 | — | — | |
| Propylene Glycol SCHEMBL4337036 | 0.87 | TDP1 (0.71) | — | |
| Lactic Acid SCHEMBL3058015 | 0.86 | TP53 (0.58) | — | |
| Methacrylic Acid SCHEMBL21905375 | 0.85 | TDP1 (0.46) | — | |
| Methacrylic Acid SCHEMBL28122889 | 0.85 | TDP1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689058-B | Treatment and prevention of sleep disorders | 普渡制药公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-108017550-B | Production process of 3-amino-1, 2-propylene glycol | 内蒙古圣氏化学股份有限公司 | 2021-11-05 | — | — | CN | disclosed |
| CN-111601591-A | Treatment and prevention of sleep disorders | 普渡制药公司 | 2020-08-28 | — | — | CN | disclosed |
| CN-110785165-A | Targeted therapeutic agents | 塔弗达治疗有限公司 | 2020-02-11 | — | — | CN | disclosed |
| CN-110559446-A | Targeted therapeutics | 马德里加尔制药公司 | 2019-12-13 | — | — | CN | disclosed |
| CN-110075069-A | Include activating agent-calcium phosphate granules compound dermal delivery composition and its application | 实验室护肤股份有限公司 | 2019-08-02 | — | — | CN | disclosed |
| CN-106074582-A | 4 cyano group β D glucoside compounds purposes in the medicine preparing treatment anxiety neurosis | 昆明学院 | 2016-11-09 | — | — | CN | disclosed |
| CN-105919945-A | Activator-loaded uniform, rigid, spherical and nano-porous calcium phosphate particles as well as preparing and using methods thereof | 实验室护肤股份有限公司 | 2016-09-07 | — | — | CN | disclosed |
| CN-103298958-B | Capsule for collecting nonferrous metal and method for collecting nonferrous metal | MORISHITA JINTAN CO.,LTD. (JP) | 2015-11-25 | — | — | CN | disclosed |
| CN-104208718-A | Glutathione-based drug delivery system | TO BBB HOLDING B V | 2014-12-17 | — | — | CN | disclosed |
| CN-101287411-A | Medication information system | PROTEUS BIOMEDICAL INC (US) | 2008-10-15 | — | — | CN | disclosed |
| CN-100393713-C | Therapeutic agents useful for treating pain | EURO CELTIQUE SA (LU) | 2008-06-11 | — | — | CN | disclosed |
| CN-1835751-A | therapeutic agent for treating pain | EURO CELTIQUE SA (LU) | 2006-09-20 | — | — | CN | disclosed |
| CN-1753890-A | Benzoxazole piperazine derivatives with MGLUR 1-and MGLUR 5-antagonistic activity | EURO CELTIQUE SA (LU) | 2006-03-29 | — | — | CN | disclosed |
| CN-1701071-A | Therapeutic agents useful for treating pain | EURO CELTIQUE SA (LU) | 2005-11-23 | — | — | CN | disclosed |
| CN-1678585-A | therapeutic agent for treating pain | EURO CELTIQUE SA (LU) | 2005-10-05 | — | — | CN | disclosed |
| US-6359079-B1 | FOR COATING POLYESTER, POLYPROPYLENE, POLYETHYLENE, COTTON, POLYAMIDE OR POLYARAMID FABRIC OR FIBER | STEPAN COMPANY | 2002-03-19 | — | — | US | disclosed |
| US-6001935-A | AMINE MODIFIED POLYETHER AND HYDROPHILIC POLYESTERS | STEPHAN COMPANY (US) | 1999-12-14 | — | — | US | disclosed |
| EP-0946811-A1 | DURABLE HYDROPHILIC POLYMER COATINGS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998027263-A1 | DURABLE HYDROPHILIC POLYMER COATINGS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-06-25 | — | — | WO | disclosed |