Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.51 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.45 |
| ▸ | BRD7 | Q9NPI1 | 2/20 | 0.45 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.37 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31438401 | 0.79 | BRD9 (0.56) | ERN1BRD9BRD7PLAUPOLB | |
| SCHEMBL17276010 | 0.79 | BRD9 (0.56) | ERN1BRD9BRD7PLAUPOLB | |
| SCHEMBL13500512 | 0.75 | BRD9 (0.47) | ERN1BRD9BRD7POLBTDP1 | |
| SCHEMBL2037315 | 0.74 | ERN1 (0.49) | ERN1BRD9BRD7PLAUPOLB | |
| SCHEMBL18717129 | 0.73 | ERN1 (0.76) | ERN1BRD9BRD7 | |
| SCHEMBL656848 | 0.71 | POLB (0.50) | ERN1BRD9BRD7PLAUPOLB | |
| SCHEMBL30054640 | 0.71 | POLB (0.50) | ERN1BRD9BRD7PLAUPOLB | |
| SCHEMBL2614933 | 0.70 | PDE10A (0.48) | ERN1BRD9BRD7PLAUPOLB | |
| SCHEMBL2035550 | 0.70 | BRD9 (0.46) | ERN1BRD9BRD7PLAUPOLB | |
| SCHEMBL2083715 | 0.70 | CYP1A2 (0.52) | ERN1BRD9BRD7PLAUPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355653-B1 | DRUG AND CARRIER FOR ANTIALLERGENS, BRAIN DISORDERS AND NEUROTRANSMITTERS | HOFFMANN-LA ROCHE INC. | 2002-03-12 | — | — | US | disclosed |