Sugi Predict

Sugi Predict / Compounds / SCHEMBL7708709

SCHEMBL7708709

SCHEMBL7708709

Cc1ccc(=O)n(CCOc2ccc(CC(Nc3ccccc3C(=O)c3ccccc3)C(=O)O)cc2)n1.O=C(c1ccccc1)c1ccccc1NC(Cc1ccc(OCCc2cccnc2)cc1)C(=O)O

nearest known ligand 0.83

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ PPARG P37231 20/20 0.83
▸ PPARA Q07869 4/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2786728 0.91 PPARG (1.00) PPARGPPARA
SCHEMBL2786404 0.87 PPARG (0.74) PPARGPPARA
SCHEMBL7705701 0.78 PPARG (1.00) PPARGPPARA
SCHEMBL2785529 0.77 PPARG (1.00) PPARGPPARA
SCHEMBL4643282 0.77 PPARG (0.63) PPARGPPARA
SCHEMBL4643296 0.77 PPARG (0.63) PPARGPPARA
SCHEMBL14274949 0.77 PPARG (0.64) PPARGPPARA
SCHEMBL4644942 0.76 PPARG (0.62) PPARGPPARA
SCHEMBL4644927 0.76 PPARG (0.62) PPARGPPARA
SCHEMBL4645753 0.76 PPARG (0.64) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3255930-B2 — — 2002-02-12 — — JP claimed
JP-2000507216-A — — 2000-06-13 — — JP claimed
EP-0888317-A1 SUBSTITUTED 4-HYDROXY-PHENYLALCANOIC ACID DERIVATIVES WITH AGONIST ACTIVITY TO PPAR-GAMMA GLAXO GROUP LIMITED (GB) 1999-01-07 — — EP claimed
WO-1997031907-A1 SUBSTITUTED 4-HYDROXY-PHENYLALCANOIC ACID DERIVATIVES WITH AGONIST ACTIVITY TO PPAR-GAMMA GLAXO GROUP LIMITED (GB) 1997-09-04 — — WO claimed
EP-0888317-A1 SUBSTITUTED 4-HYDROXY-PHENYLALCANOIC ACID DERIVATIVES WITH AGONIST ACTIVITY TO PPAR-GAMMA GLAXO GROUP LIMITED (GB) 1999-01-07 — — EP disclosed
WO-1997031907-A1 SUBSTITUTED 4-HYDROXY-PHENYLALCANOIC ACID DERIVATIVES WITH AGONIST ACTIVITY TO PPAR-GAMMA GLAXO GROUP LIMITED (GB) 1997-09-04 — — WO disclosed